We deliver silicon-based probes comprising typically 8 to 64 electrodes per shaft. The electrodes can be positioned in a tetrode configuration, a laminar distribution or randomly along the probe shafts. In general, we use Platium (Pt), Iridium Oxide (IrOx) or Gold (Au) as electrode material.
Aside from standard silicon probe layouts listed in our catalog, we also offer custom-design probes. Please contact us in case you would like to receive more information on our custom-design probe service.
All probe shafts can be equipped with a pointy tip feature instead of the standard chisel-shape tip. The pointy tip significantly reduces any dimpling effects during probe insertion even when using an additional artificial silicone dura stacked on top of the dura mater. There is no need to cut or puncture the dura which decreases the risk on bleeding and infection.
Another key feature of our silicon probe technology is the flexibility. Our silicon probes have had a special treatment which makes them bend once the probe hits a rigid obstacle. The flexible feature perfectly suitable to load the silicon-based probe in existing hyperdrives such as the Kloosterman drive (Michon et al.) or the Flex drive of Open-Ephys.
Once removing the probe always prevent that any organic residue can dry-out on the probe shaft, flush it with deionized water, alcohol and rinse again with deionized water. Next, hold the silicon shaft in 1% tergazyme solution for 30-60min and flush it with deionized water. The silicon shaft should be shiny and is ready to use again.
We do have probe layouts available for all types of experimental setups, however those can be differentiated in three main categories: active, chronic and semi-chronic probe layouts. The three different probe layouts are summarized below.
The silicon probe is assembled onto a rigid printed circuit board (PCB), which can be attached onto the stereotactic frame and is often used in acute setups. Depending on the amount of channels, different connectors can be used such as DIL, MOLC, Micro Omnetics, etc... The different PCB layouts can be found when selecting the acute check-box in our digital probe catalog.
The silicon probe is assembled onto a 3-cm-long ultra-flexible polyimide cable designed to interface with a ZIF-plug or Omnetics connector. The chronic layout is perfectly suited for chronic experiments and setups where it is recommended to mechanically decouple the connector from the silicon probe and could be of interest for bigger size animal-models. Second, all mechanical vibrations impacting the connector are not propagated to the electrodes.
The silicon probe is assembled as close to the connector as possible. This is the most compact probe layout and perfectly suitable for small-animal models in acute and chronic setups. This probe layout typically makes use of nano Omnetics connectors and the different layouts can be found when selecting the semi-chronic check-box in our digital probe catalog.